Measurement properties of the EQ-5D in children and adolescents: a systematic review protocol
Measurement properties of the EQ-5D in children and adolescents: a systematic review protocol
Data
2024
Autores
Santo, Caique de Melo do Espirito
Santos, Verônica Souza
Miyamoto, Gisela Cristiane
Chiarotto, Alessandro
Santos, Marisa
Yamato, Tiê Parma
Journal Title
Journal ISSN
Volume Title
Publisher
Systematic Reviews
Resumo
Background Although the EQ-5D instruments have been initially designed for adult populations, there are new
studies evaluating and applying these instruments to children and adolescents. The EuroQol Group adapted and cre-
ated two versions designed for these groups, i.e., the EQ-5D-Y versions. The measurement properties of the EQ-5D
have been systematically reviewed in diferent health conditions. However, there is a lack of a proper systematic
assessment including the studies’ risk of bias and focusing on recent studies assessing the EQ-5D instruments in chil-
dren and adolescents. The lack of a systematic assessment of the EQ-5D versions does not allow us to have a com-
prehensive evaluation of the validity, reliability, and responsiveness of these instruments among children and adoles-
cents. This systematic review aims to critically appraise and summarize the evidence on the measurement properties
of the EQ-5D instruments (self-reported version – answered by children and adolescents; and proxy versions – ver-
sions reported by parents, caregivers, or health professionals) in children and adolescents.
Methods A systematic review searching the following electronic databases: MEDLINE, EMBASE, CINAHL, EconLit,
National Health Service Economic Evaluation Database (NHS-EED), Health Technology Assessment (HTA) database.
Two independent reviewers will screen titles and abstracts and select full texts for eligibility. The COnsensus-based
Standards for the selection of health Measurement INstruments (COSMIN) methodology will be followed to conduct
three main assessment steps: risk of bias, quality criteria for measurement properties, and evidence synthesis.
Discussion This systematic review will provide comprehensive information about the evidence regarding the meas-
urement properties of EQ-5D instruments in children and adolescents of diferent settings and countries.
Description
Palavras-chave
Measurement properties, Children and adolescents, EQ-5D, Health-related quality of life.
Citação
Espirito Santo CM, Santos VS, Miyamoto GC, Chiarotto A, Santos M, Yamato TP. Measurement properties of the EQ-5D in children and adolescents: a systematic review protocol. Syst Rev. 2024 Jan 5;13(1):18. doi: 10.1186/s13643-023-02443-7.