Measurement properties of the EQ-5D in children and adolescents: a systematic review protocol

dc.contributor.authorSanto, Caique de Melo do Espirito
dc.contributor.authorSantos, Verônica Souza
dc.contributor.authorMiyamoto, Gisela Cristiane
dc.contributor.authorChiarotto, Alessandro
dc.contributor.authorSantos, Marisa
dc.contributor.authorYamato, Tiê Parma
dc.date.accessioned2025-02-06T15:11:57Z
dc.date.available2025-02-06T15:11:57Z
dc.date.issued2024
dc.description.abstractBackground Although the EQ-5D instruments have been initially designed for adult populations, there are new studies evaluating and applying these instruments to children and adolescents. The EuroQol Group adapted and cre- ated two versions designed for these groups, i.e., the EQ-5D-Y versions. The measurement properties of the EQ-5D have been systematically reviewed in diferent health conditions. However, there is a lack of a proper systematic assessment including the studies’ risk of bias and focusing on recent studies assessing the EQ-5D instruments in chil- dren and adolescents. The lack of a systematic assessment of the EQ-5D versions does not allow us to have a com- prehensive evaluation of the validity, reliability, and responsiveness of these instruments among children and adoles- cents. This systematic review aims to critically appraise and summarize the evidence on the measurement properties of the EQ-5D instruments (self-reported version – answered by children and adolescents; and proxy versions – ver- sions reported by parents, caregivers, or health professionals) in children and adolescents. Methods A systematic review searching the following electronic databases: MEDLINE, EMBASE, CINAHL, EconLit, National Health Service Economic Evaluation Database (NHS-EED), Health Technology Assessment (HTA) database. Two independent reviewers will screen titles and abstracts and select full texts for eligibility. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology will be followed to conduct three main assessment steps: risk of bias, quality criteria for measurement properties, and evidence synthesis. Discussion This systematic review will provide comprehensive information about the evidence regarding the meas- urement properties of EQ-5D instruments in children and adolescents of diferent settings and countries.
dc.identifier.citationEspirito Santo CM, Santos VS, Miyamoto GC, Chiarotto A, Santos M, Yamato TP. Measurement properties of the EQ-5D in children and adolescents: a systematic review protocol. Syst Rev. 2024 Jan 5;13(1):18. doi: 10.1186/s13643-023-02443-7.
dc.identifier.otherDOI: 10.1186/s13643-023-02443-7
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/809
dc.language.isoen
dc.publisherSystematic Reviews
dc.subjectMeasurement propertiesen
dc.subjectChildren and adolescentsen
dc.subjectEQ-5Den
dc.subjectHealth-related quality of life.en
dc.titleMeasurement properties of the EQ-5D in children and adolescents: a systematic review protocol
dc.typeArticle
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