Brazilian breast cancer patient- reported outcomes: What really matters for these women
Brazilian breast cancer patient- reported outcomes: What really matters for these women
Data
2022
Autores
Silva, Aline Silveira
França, Ana Cláudia Wekmuller
Padilla, Matheus Piccin
Macedo, Luana Schroeder
Magliano, Carlos Alberto da Silva
Santos, Marisa da Silva
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers in Medical Technology
Resumo
Introduction: Patient-Reported Outcomes (PRO) are directly reported by the
patient without interpretation of the patient’s response by a clinician or
anyone else and pertains to the patient’s health, quality of life, or functional
status associated with health care or treatment. It can provide patients’
perspectives regarding treatment benefit and harm beyond survival and are
often the outcomes of most importance to patients. This study aims to
describe and analyze outcomes reported by Brazilian women diagnosed with
breast cancer and rank the most important attributes for these patients.
Methods: Observational descriptive study composed of exploratory interviews
followed by online questionnaires applied to a convenience sample of women
diagnosed with breast cancer.
Results: Twelve women were interviewed to explore the main outcomes and
preferences about their treatments, such as the most common side effects and
the most impacted aspects of life after diagnosis and BC treatment.
Psychological, emotional, and sexual impacts were frequently described as
impacted aspects. Fifty-three women, from all the five Brazilian regions,
answered the online questionnaire. Following an order of importance ranking,
the following outcomes were chosen, respectively: overall survival, progression-
free survival; and quality of life. The treatment effects that were considered less
important, among this sample, were pain and adverse events.
Conclusions: Thinking about expanding the therapeutic quality of users, it is
essential to take into account the experiences of patients. PRO is a trend in
current research to achieve this goal, in order to influence the decisions of HTA
agencies about the importance of valuing outcomes that affect patients’ lives.
Description
Palavras-chave
patient-reported outcomes, PRO, PROs, patient preferences, preference study, breast cancer, patient perspective, patient experience
Citação
Silva AS, França ACW, Padilla MP, Macedo LS, Magliano CADS, Santos MDS. Brazilian breast cancer patient-reported outcomes: What really matters for these women. Front Med Technol. 2022 Nov 21;4:809222. doi: 10.3389/fmedt.2022.809222.