Cost-Effectiveness of Procedures for Treatment of Ostium Secundum Atrial Septal Defects Occlusion Comparing Conventional Surgery and Septal Percutaneous Implant

dc.contributor.authorCosta, Márcia Gisele Santos da
dc.contributor.authorSantos, Marisa da Silva
dc.contributor.authorSarti, Flávia Mori
dc.contributor.authorSenna, Kátia Marie Simões e
dc.contributor.authorTura, Bernardo Rangel
dc.contributor.authorGoulart, Marcelo Correia
dc.date.accessioned2022-09-14T17:45:43Z
dc.date.available2022-09-14T17:45:43Z
dc.date.issued2014
dc.description.abstractObjectives: The study performs a cost-effectiveness analysis of procedures for atrial septal defects occlusion, comparing conventional surgery to septal percutaneous implant. Methods: A model of analytical decision was structured with symmetric branches to estimate cost-effectiveness ratio between the procedures. The decision tree model was based on evidences gathered through meta-analysis of literature, and validated by a panel of specialists. The lower number of surgical procedures performed for atrial septal defects occlusion at each branch was considered as the effectiveness outcome. Direct medical costs and probabilities for each event were inserted in the model using data available from Brazilian public sector database system and information extracted from the literature review, using micro-costing technique. Sensitivity analysis included price variations of percutaneous implant. Results: The results obtained from the decision model demonstrated that the percutaneous implant was more cost effective in cost-effectiveness analysis at a cost of US 8,936.34 with a reduction in the probability of surgery occurrence in 93% of the cases. Probability of atrial septal communication occlusion and cost of the implant are the determinant factors of costeffectiveness ratio. Conclusions: The proposal of a decision model seeks to fill a void in the academic literature. The decision model proposed includes the outcomes that present major impact in relation to the overall costs of the procedure. The atrial septal defects occlusion using percutaneous implant reduces the physical and psychological distress to the patients in relation to the conventional surgery, which represent intangible costs in the context of economic evaluation.
dc.identifier.citationCosta MGS, Santos MS, Sarti FM, Senna KMS, Tura BR, Goulart MC. Cost-Effectiveness of Procedures for Treatment of Ostium Secundum Atrial Septal Defects Occlusion Comparing Conventional Surgery and Septal Percutaneous Implant. PLoS ONE. 2014;9(10):e108966. Doi: 10.1371/journal.pone.0108966.
dc.identifier.otherDOI: 10.1371/journal.pone.0108966
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/283
dc.language.isoen
dc.publisherPloS One
dc.subjectOstium Secundum Atrial Septal Defects Occlusionen
dc.subjectSeptal Percutaneous Implanten
dc.subjectCost-Effectivenessen
dc.subject.meshProstheses and Implants / economicsen
dc.subject.meshHumansen
dc.subject.meshHeart Septal Defects, Atrial / therapyen
dc.subject.meshHeart Septal Defects, Atrial / surgeryen
dc.subject.meshHeart Septal Defects, Atrial / economicsen
dc.subject.meshDecision Support Techniquesen
dc.subject.meshCost-Benefit Analysisen
dc.subject.meshBrazilen
dc.subject.meshAtrial Septum / surgeryen
dc.subject.meshProstheses and Implants / economicsen
dc.subject.meshHumansen
dc.subject.meshHeart Septal Defects, Atrial / therapyen
dc.subject.meshHeart Septal Defects, Atrial / surgeryen
dc.subject.meshHeart Septal Defects, Atrial / economicsen
dc.subject.meshDecision Support Techniquesen
dc.subject.meshCost-Benefit Analysisen
dc.subject.meshBrazilen
dc.subject.meshAtrial Septum / surgeryen
dc.titleCost-Effectiveness of Procedures for Treatment of Ostium Secundum Atrial Septal Defects Occlusion Comparing Conventional Surgery and Septal Percutaneous Implant
dc.typeArticle
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