The Association Between Physical Performance and Health-Related Quality of Life Based on the EQ-5D-3L Questionnaire in Patients With Chagas Disease

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dc.contributor.authorLins, Wylisson Marcelo Almeida
dc.contributor.authorTura, Bernardo Rangel
dc.contributor.authorKasal, Daniel Arhur
dc.date.accessioned2023-12-18T14:54:53Z
dc.date.available2023-12-18T14:54:53Z
dc.date.issued2021
dc.description.abstractObjectives: Chagas disease (CD) is a chronic disease to millions worldwide, and many patients develop heart disease. In addition, they are part of an aging population. These characteristics can be associated with a reduction in physical performance and health-related quality of life (HRQoL). This study evaluated HRQoL, and the relationship between physical performance and HRQoL in patients with chronic CD. Methods: We used the 3-level version of EuroQol 5-dimensional questionnaire (EQ-5D-3L), with the visual analog scale (VAS). Physical performance was measured with 30-s chair-stand test (30sCST) and timed up and go test (TUGT). Results: Sixty-three patients were evaluated. The majority were women (68.2%) aged 67.7 ± 9.7 years. Overall EQ-5D-3L utility index was 0.65 ± 0.28, and VAS score was 68.4 ± 25.1. Most patients with intermediate and high performance in 30sCST referred no problems in the domains "mobility," "usual activities," and "pain/feeling ill" (P < .001, P = .01, and P = .025, respectively). In a similar way, most patients with intermediate and high performance in TUGT referred no problems in "mobility" (P < .0001) and "usual activities" (P = .001). Higher performance in both tests was associated with higher overall EQ-5D-3L utility and VAS scores. HRQoL measured by EQ-5D-3L was associated with physical status in a cohort of patients with chronic CD. The results underscore the contribution of physical performance, measured by 2 inexpensive and safe physical tests, to HRQoL in these patients. Conclusion: Strategies aiming the improvement of HRQoL in patients with CD may focus on mobility skills and force. Future studies evaluating interventions in physical performance should be a priority in these patients.
dc.identifier.citationAlmeida Lins WM, Tura BR, Kasal DA. The Association Between Physical Performance and Health-Related Quality of Life Based on the EQ-5D-3L Questionnaire in Patients With Chagas Disease. Value Health Reg Issues. 2021 Dec;26:191-196. doi: 10.1016/j.vhri.2021.09.002. Epub 2021 Oct 30. PMID: 34757310.
dc.identifier.otherDOI: 10.1016/j.vhri.2021.09.002
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/383
dc.language.isoen
dc.publisherValue in Health Regional Issues
dc.subjectTimed up and go testen
dc.subjectHealth-related quality of lifeen
dc.subjectChagas diseaseen
dc.subject30-s chair-stand testen
dc.subject.meshQuality of Lifeen
dc.subject.meshPostural Balanceen
dc.subject.meshPhysical Functional Performanceen
dc.subject.meshMaleen
dc.subject.meshHumansen
dc.subject.meshFemaleen
dc.subject.meshChagas Diseaseen
dc.subject.meshAgeden
dc.subject.meshSurveys and Questionnairesen
dc.subject.meshTime and Motion Studiesen
dc.titleThe Association Between Physical Performance and Health-Related Quality of Life Based on the EQ-5D-3L Questionnaire in Patients With Chagas Disease
dc.typeArticle
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