ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents

dc.contributor.authorBarros, Bruna de Siqueira
dc.contributor.authorKuschnir, Maria Cristina Caetano
dc.contributor.authorKuschnir, Fabio Chigres
dc.contributor.authorJordão, Erica Azevedo de Oliveira Costa
dc.date.accessioned2024-10-29T18:23:18Z
dc.date.available2024-10-29T18:23:18Z
dc.date.issued2022
dc.description.abstractObjective: To investigate the association between oral contraceptive use and cardiovascular risks, including metabolic syndrome and their components in Brazilian adolescents. Method: This study used data from the Study of Cardiovascular Risks in Adolescents (Estudo de Riscos Cardiovasculares em Adolescentes - ERICA), a nationwide, cross-sectional, school- based study with individuals aged 12-17 years. Sociodemographic variables and OC use were assessed by a self-administered questionnaire. International Diabetes Federation cri- teria were used to define metabolic syndrome. Descriptive statistics were reported as prev- alence and their respective confidence interval of 95% of oral contraceptives according to variables. Logistic regression was performed. Crude and adjusted odds ratios were calculated. Results: This subsample was composed of 22,682 female adolescents, of which 12.65% reported using oral contraceptives and their use was associated with hypertension and hypertriglyceride- mia. These associations remained statistically significant after adjusting for age, school region, race, and tobacco use with an increase of 2.68 (1.66 4.32) and 3.45 (2.56 4.65) times, respectively. Conclusion: The present study was the first to examine the association between the use of oral contraceptives and cardiovascular risk factors among the largest number of female Brazilian adolescents. This method was significantly associated with hypertension, hypertriglyceridemia. Teenagers using oral contraceptives should be monitored for side effects, including blood pressure measurements and advised to avoid smoking.
dc.identifier.citationBarros BS, Kuschnir MCC, Kuschnir FC, Jordão EAOC. ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents. Jornal de Pediatria. 2022 jan-feb;98(1):53-59. doi: 10.1016/j.jped.2021.03.006
dc.identifier.otherDOI: 10.1016/j.jped.2021.03.006
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/550
dc.language.isoen
dc.publisherJornal de Pediatria
dc.subjectContraceptiveen
dc.subjectOralen
dc.subjectAdolescenten
dc.subjectCardiovascular risken
dc.subjectMetabolic syndromeen
dc.subjectHypertensionen
dc.subjectHypertriglyceridemiaen
dc.titleERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents
dc.typeArticle
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