ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents
ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents
Data
2022
Autores
Barros, Bruna de Siqueira
Kuschnir, Maria Cristina Caetano
Kuschnir, Fabio Chigres
Jordão, Erica Azevedo de Oliveira Costa
Journal Title
Journal ISSN
Volume Title
Publisher
Jornal de Pediatria
Resumo
Objective: To investigate the association between oral contraceptive use and cardiovascular
risks, including metabolic syndrome and their components in Brazilian adolescents.
Method: This study used data from the Study of Cardiovascular Risks in Adolescents (Estudo
de Riscos Cardiovasculares em Adolescentes - ERICA), a nationwide, cross-sectional, school-
based study with individuals aged 12-17 years. Sociodemographic variables and OC use
were assessed by a self-administered questionnaire. International Diabetes Federation cri-
teria were used to define metabolic syndrome. Descriptive statistics were reported as prev-
alence and their respective confidence interval of 95% of oral contraceptives according to
variables. Logistic regression was performed. Crude and adjusted odds ratios were
calculated.
Results: This subsample was composed of 22,682 female adolescents, of which 12.65% reported
using oral contraceptives and their use was associated with hypertension and hypertriglyceride-
mia. These associations remained statistically significant after adjusting for age, school region,
race, and tobacco use with an increase of 2.68 (1.66 4.32) and 3.45 (2.56 4.65) times,
respectively.
Conclusion: The present study was the first to examine the association between the use of oral
contraceptives and cardiovascular risk factors among the largest number of female Brazilian
adolescents. This method was significantly associated with hypertension, hypertriglyceridemia.
Teenagers using oral contraceptives should be monitored for side effects, including blood pressure measurements and advised to avoid smoking.
Description
Palavras-chave
Contraceptive, Oral, Adolescent, Cardiovascular risk, Metabolic syndrome, Hypertension, Hypertriglyceridemia
Citação
Barros BS, Kuschnir MCC, Kuschnir FC, Jordão EAOC. ERICA: cardiovascular risks associated with oral contraceptive use among Brazilian adolescents. Jornal de Pediatria. 2022 jan-feb;98(1):53-59. doi: 10.1016/j.jped.2021.03.006