Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents
Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents
dc.contributor.author | Fernandes, Rita de Cássia Lima | |
dc.contributor.author | Teló, Gabriela H. | |
dc.contributor.author | Cureau, Felipe V. | |
dc.contributor.author | Barufaldi, Laura A. | |
dc.contributor.author | Kuschnir, Maria Cristina C. | |
dc.contributor.author | Schaan, Beatriz D. | |
dc.contributor.author | Szklo, Moyses | |
dc.contributor.author | Bloch, Katia V. | |
dc.date.accessioned | 2024-10-29T19:35:24Z | |
dc.date.available | 2024-10-29T19:35:24Z | |
dc.date.issued | 2017 | |
dc.description.abstract | To evaluate the prevalence of elevated glycated haemoglobin (HbA1c) levels in a pop- ulation of adolescents participating in the Study of Cardiovascular Risk in Adolescents. Methods: This is a school-based cross-sectional study based on a complex sample of ado- lescents 12–17 years old representative at the national and macro-regional levels and for each Brazilian state capital. Blood was collected in schools and then evaluated in a single laboratory. HbA1c levels were considered elevated if P5.7% (39 mmol/mol) and were ana- lyzed according to sex, age, macro-region, type of school, skin color, and nutritional status. Results: Data from 37,804 adolescents were analyzed. The mean level of HbA1c was 5.4% (95%CI 5.4–5.4) (36 mmol/mol [95%CI 36–36]), and 20.5% (95%CI 19.1–22.0) of adolescents presented values P5.7% (P39 mmol/mol). Among males, 23.6% (95%CI 21.8–25.6) showed elevated HbA1c levels compared to 17.5% (95%CI 15.9–19.2) observed in females. The preva- lence of elevated levels of HbA1c was higher in adolescents with black skin color (27.6%; 95%CI 23.2–32.4) vs. white skin color (16.9%; 95%CI 15.4–18.5), and higher in those who stud- ied in public schools (21.6%; 95%CI 20.0–23.4) vs. private schools (16.7%; 95%CI 14.7–19.0). Among obese adolescents, 29.7% (95%CI 25.4–34.3) had elevated levels of HbA1c, compared to 19.3% (95%CI 18.0–20.7) in normal weight students and 19.7% (95%CI 17.1–22.6) in over- weight adolescents. Conclusions: Obese male adolescents of lower socioeconomic status had a higher preva- lence of elevated HbA1c levels. Our findings highlight the importance of focusing on this high risk group for interventions to prevent diabetes. | |
dc.identifier.citation | Fernandes RCL, Teló GH, Cureau FV, Barufaldi LA, Kuschnir MC, Schaan BD, Szklo M, Bloch KV. Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents. Diabetes Res Clin Pract. 2017 Mar;125:1-9. doi: 10.1016/j.diabres.2017.01.003 | |
dc.identifier.other | DOI: 10.1016/j.diabres.2017.01.003 | |
dc.identifier.uri | https://dspace.inc.saude.gov.br/handle/123456789/554 | |
dc.language.iso | en | |
dc.publisher | Diabetes Research and Clinical Practice | |
dc.subject | Adolescent | en |
dc.subject | Hemoglobin A | en |
dc.subject | glycosylated | en |
dc.subject | Obesity | en |
dc.subject | Diabetes mellitus | en |
dc.subject | Developing countries | en |
dc.title | Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents | |
dc.type | Article |
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