Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents

dc.contributor.authorFernandes, Rita de Cássia Lima
dc.contributor.authorTeló, Gabriela H.
dc.contributor.authorCureau, Felipe V.
dc.contributor.authorBarufaldi, Laura A.
dc.contributor.authorKuschnir, Maria Cristina C.
dc.contributor.authorSchaan, Beatriz D.
dc.contributor.authorSzklo, Moyses
dc.contributor.authorBloch, Katia V.
dc.date.accessioned2024-10-29T19:35:24Z
dc.date.available2024-10-29T19:35:24Z
dc.date.issued2017
dc.description.abstractTo evaluate the prevalence of elevated glycated haemoglobin (HbA1c) levels in a pop- ulation of adolescents participating in the Study of Cardiovascular Risk in Adolescents. Methods: This is a school-based cross-sectional study based on a complex sample of ado- lescents 12–17 years old representative at the national and macro-regional levels and for each Brazilian state capital. Blood was collected in schools and then evaluated in a single laboratory. HbA1c levels were considered elevated if P5.7% (39 mmol/mol) and were ana- lyzed according to sex, age, macro-region, type of school, skin color, and nutritional status. Results: Data from 37,804 adolescents were analyzed. The mean level of HbA1c was 5.4% (95%CI 5.4–5.4) (36 mmol/mol [95%CI 36–36]), and 20.5% (95%CI 19.1–22.0) of adolescents presented values P5.7% (P39 mmol/mol). Among males, 23.6% (95%CI 21.8–25.6) showed elevated HbA1c levels compared to 17.5% (95%CI 15.9–19.2) observed in females. The preva- lence of elevated levels of HbA1c was higher in adolescents with black skin color (27.6%; 95%CI 23.2–32.4) vs. white skin color (16.9%; 95%CI 15.4–18.5), and higher in those who stud- ied in public schools (21.6%; 95%CI 20.0–23.4) vs. private schools (16.7%; 95%CI 14.7–19.0). Among obese adolescents, 29.7% (95%CI 25.4–34.3) had elevated levels of HbA1c, compared to 19.3% (95%CI 18.0–20.7) in normal weight students and 19.7% (95%CI 17.1–22.6) in over- weight adolescents. Conclusions: Obese male adolescents of lower socioeconomic status had a higher preva- lence of elevated HbA1c levels. Our findings highlight the importance of focusing on this high risk group for interventions to prevent diabetes.
dc.identifier.citationFernandes RCL, Teló GH, Cureau FV, Barufaldi LA, Kuschnir MC, Schaan BD, Szklo M, Bloch KV. Prevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents. Diabetes Res Clin Pract. 2017 Mar;125:1-9. doi: 10.1016/j.diabres.2017.01.003
dc.identifier.otherDOI: 10.1016/j.diabres.2017.01.003
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/554
dc.language.isoen
dc.publisherDiabetes Research and Clinical Practice
dc.subjectAdolescenten
dc.subjectHemoglobin Aen
dc.subjectglycosylateden
dc.subjectObesityen
dc.subjectDiabetes mellitusen
dc.subjectDeveloping countriesen
dc.titlePrevalence of high HbA1c levels in Brazilian adolescents: The Study of Cardiovascular Risk in Adolescents
dc.typeArticle
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