Effects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial

Página do item simplificado
dc.contributor.authorSantos, Elisa M. dos
dc.contributor.authorMoreira, Annie S. B.
dc.contributor.authorHuguenin, Grazielle V. B.
dc.contributor.authorTibiriçá, Eduardo
dc.contributor.authorLorenzo, Andrea de
dc.date.accessioned2025-08-01T14:39:46Z
dc.date.available2025-08-01T14:39:46Z
dc.date.issued2023
dc.description.abstractHeart failure (HF) is associated with a reduction of skeletal muscle mass. Whey protein isolate (WPI) has been beneficial in increasing muscle mass and strength, in addition to improving body composition. The goal of this research was to evaluate the effect of WPI on the body composition, muscle mass, and strength of chronic HF patients. For this purpose, twenty-five patients of both genders with predominantly NYHA I functional class and a median age of 65.5 (60.5–71.0) years were used to conduct a randomized, single-blind, placebo-controlled clinical trial and received 30 g per day of WPI for 12 weeks. Anthropometric measurements, body composition analysis, and biochemical exams were performed at the beginning and end of the study. An increase in skeletal muscle mass was observed in the intervention group after 12 weeks. A reduction in waist circumference, body fat percentage, and an increase in skeletal muscle index was observed when compared to the placebo group. No significant effect on muscle strength was observed after 12 weeks of intervention. These data demonstrate that WPI consumption contributed to the increase of skeletal muscle mass, strength, and reduction of body fat in HF patients.
dc.identifier.citationSantos EM, Moreira ASB, Huguenin GVB, Tibiriça E, de Lorenzo A. Effects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial. Nutrients. 2023 May 16;15(10):2320. doi: 10.3390/nu15102320.
dc.identifier.otherDOI: 10.3390/nu15102320
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/931
dc.language.isoen
dc.publisherNutrients
dc.subjectheart failureen
dc.subjectDieten
dc.subjectWhey Proteinsen
dc.subjectMuscle strengthen
dc.subjectRandomized clinical trial.en
dc.titleEffects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial
dc.typeArticle
Arquivos
Original bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.alt
Nome:
Santos EM et al_Nutriens_PDF.pdf
Tamanho:
1.78 MB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
License bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.placeholder
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed to upon submission
Descrição:
Baixar
Coleções
Artigos Mestrado CC
Produção Bibliográfica