Effects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial
Effects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial
Data
2023
Autores
Santos, Elisa M. dos
Moreira, Annie S. B.
Huguenin, Grazielle V. B.
Tibiriçá, Eduardo
Lorenzo, Andrea de
Journal Title
Journal ISSN
Volume Title
Publisher
Nutrients
Resumo
Heart failure (HF) is associated with a reduction of skeletal muscle mass. Whey protein
isolate (WPI) has been beneficial in increasing muscle mass and strength, in addition to improving
body composition. The goal of this research was to evaluate the effect of WPI on the body composition,
muscle mass, and strength of chronic HF patients. For this purpose, twenty-five patients of both
genders with predominantly NYHA I functional class and a median age of 65.5 (60.5–71.0) years were
used to conduct a randomized, single-blind, placebo-controlled clinical trial and received 30 g per day
of WPI for 12 weeks. Anthropometric measurements, body composition analysis, and biochemical
exams were performed at the beginning and end of the study. An increase in skeletal muscle mass
was observed in the intervention group after 12 weeks. A reduction in waist circumference, body fat
percentage, and an increase in skeletal muscle index was observed when compared to the placebo
group. No significant effect on muscle strength was observed after 12 weeks of intervention. These
data demonstrate that WPI consumption contributed to the increase of skeletal muscle mass, strength,
and reduction of body fat in HF patients.
Description
Palavras-chave
heart failure, Diet, Whey Proteins, Muscle strength, Randomized clinical trial.
Citação
Santos EM, Moreira ASB, Huguenin GVB, Tibiriça E, de Lorenzo A. Effects of whey protein isolate on body composition, muscle mass, and strength of chronic heart failure patients: a randomized clinical trial. Nutrients. 2023 May 16;15(10):2320. doi: 10.3390/nu15102320.