Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study

Página do item simplificado
dc.contributor.authorKaestner, Tatiana L.
dc.contributor.authorSantos, Jamylle A. D.
dc.contributor.authorPazin, Daiane C.
dc.contributor.authorBaena, Cristina P.
dc.contributor.authorOlandoski, Marcia
dc.contributor.authorAbreu, Gabriela A.
dc.contributor.authorKuschnir, Maria Cristina C.
dc.contributor.authorBloch, Katia V.
dc.contributor.authorFaria-Neto, Jose R.
dc.date.accessioned2024-10-30T17:49:05Z
dc.date.available2024-10-30T17:49:05Z
dc.date.issued2020
dc.description.abstractBackground: Cardiovascular diseases are the leading cause of death in Brazil and worldwide. The growing incidence of obesity in children and adolescents and its association with lipid abnormalities may worsen this scenario, mainly in developing countries where obesity has reached epidemic levels. Dyslipidemias have several patterns, and the combination of some lipid abnormalities may have higher atherogenic potential. Objectives: To evaluate the prevalence of single or multiple combined lipid abnormalities in adolescents and its association with nutritional status assessed by body mass index. Methods: Data were obtained from the Study of Cardiovascular Risks in Adolescents (ERICA), a school-based, national representative study with Brazilian adolescents between 12 and 17 years of age. Adolescents whose lipid profiles were available were included, and lipid abnormalities were defined as LDL-C ≥ 100 mg/dL, HDL-C < 45 mg/dL, and tryglicerides (TG) ≥ 100 mg/dL. We assessed the prevalence of single or combined lipid abnormalities and correlated this nutri- tional status with body mass index of low weight, normal, overweight, and obesity. Results: A total of 38,069 adolescents were included, with more than 24,000 of them present- ing at least one lipid abnormality (64.7%), and 3.7% showing alterations in all of them. The most prevalent combination was high TG with low HDL-C levels. The higher the BMI, the more lipid abnormalities were found. Conclusions: In this large and representative sample of Brazilian adolescents, the majority had at least one lipid abnormality. Higher BMI was associated with a higher prevalence of combined lipid abnormalities. Highlights: - There is a high prevalence of Brazilian adolescents with dyslipidemias. - BMI was associated with a higher prevalence of combined lipid abnormalities. - BMI can be considered as an indicator of the diagnosis of dyslipidemia in adolescents.
dc.identifier.citationKaestner TL, Santos JAD, Pazin DC, Baena CP, Olandoski M, Abreu GA, Kuschnir MCC, Bloch KV, Faria-Neto JR. Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study. Glob Heart. 2020 Mar 18;15(1):23. doi: 10.5334/gh.769
dc.identifier.otherDOI: 10.5334/gh.769
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/558
dc.language.isoen
dc.publisherGlobal Heart
dc.subjectdyslipidemiaen
dc.subjectadolescentsen
dc.subjectrisk factorsen
dc.subjectscreeningen
dc.titlePrevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study
dc.typeArticle
Arquivos
Original bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.alt
Nome:
Kaestner TL et al_Glob Heart.pdf
Tamanho:
701.84 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
License bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.placeholder
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed to upon submission
Descrição:
Baixar
Coleções
Produção Docente