Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study
Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study
Data
2020
Autores
Kaestner, Tatiana L.
Santos, Jamylle A. D.
Pazin, Daiane C.
Baena, Cristina P.
Olandoski, Marcia
Abreu, Gabriela A.
Kuschnir, Maria Cristina C.
Bloch, Katia V.
Faria-Neto, Jose R.
Journal Title
Journal ISSN
Volume Title
Publisher
Global Heart
Resumo
Background: Cardiovascular diseases are the leading cause of death in Brazil and worldwide.
The growing incidence of obesity in children and adolescents and its association with lipid
abnormalities may worsen this scenario, mainly in developing countries where obesity has
reached epidemic levels. Dyslipidemias have several patterns, and the combination of some lipid
abnormalities may have higher atherogenic potential.
Objectives: To evaluate the prevalence of single or multiple combined lipid abnormalities in
adolescents and its association with nutritional status assessed by body mass index.
Methods: Data were obtained from the Study of Cardiovascular Risks in Adolescents (ERICA), a
school-based, national representative study with Brazilian adolescents between 12 and 17 years
of age. Adolescents whose lipid profiles were available were included, and lipid abnormalities
were defined as LDL-C ≥ 100 mg/dL, HDL-C < 45 mg/dL, and tryglicerides (TG) ≥ 100 mg/dL.
We assessed the prevalence of single or combined lipid abnormalities and correlated this nutri-
tional status with body mass index of low weight, normal, overweight, and obesity.
Results: A total of 38,069 adolescents were included, with more than 24,000 of them present-
ing at least one lipid abnormality (64.7%), and 3.7% showing alterations in all of them. The most
prevalent combination was high TG with low HDL-C levels. The higher the BMI, the more lipid
abnormalities were found.
Conclusions: In this large and representative sample of Brazilian adolescents, the majority had
at least one lipid abnormality. Higher BMI was associated with a higher prevalence of combined
lipid abnormalities.
Highlights:
- There is a high prevalence of Brazilian adolescents with dyslipidemias.
- BMI was associated with a higher prevalence of combined lipid abnormalities.
- BMI can be considered as an indicator of the diagnosis of dyslipidemia in adolescents.
Description
Palavras-chave
dyslipidemia, adolescents, risk factors, screening
Citação
Kaestner TL, Santos JAD, Pazin DC, Baena CP, Olandoski M, Abreu GA, Kuschnir MCC, Bloch KV, Faria-Neto JR. Prevalence of Combined Lipid Abnormalities in Brazilian Adolescents and Its Association with Nutritional Status: Data from the Erica Study. Glob Heart. 2020 Mar 18;15(1):23. doi: 10.5334/gh.769