Estimating an EQ‐5D‐Y‐3L Value Set for Brazil

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dc.contributor.authorSanto, Caique Melo Espirito
dc.contributor.authorMiyamoto, Gisela Cristiane
dc.contributor.authorSantos, Verônica Souza
dc.contributor.authorBen, Ângela Jornada
dc.contributor.authorFinch, Aureliano Paolo
dc.contributor.authorRoudijk, Bram
dc.contributor.authorJesus‐Moraleida, Fabianna Resende de
dc.contributor.authorStein, Airton Tetelbom
dc.contributor.authorSantos, Marisa
dc.contributor.authorYamato, Tiê Parma
dc.date.accessioned2025-02-06T15:42:25Z
dc.date.available2025-02-06T15:42:25Z
dc.date.issued2024
dc.description.abstractIntroduction The EQ-5D-Y-3L is a generic measure of health-related quality of life in children and adolescents. Although the Brazilian-Portuguese EQ-5D-Y-3L version is available, there is no value set for it, hampering its use in economic evalu- ations. This study aimed to elicit a Brazilian EQ-5D-Y-3L value set based on preferences of the general adult population. Methods Two independent samples of adults participated in an online discrete choice experiment (DCE) survey and a composite time trade-of (cTTO) face-to-face interview. The framing was “considering your views for a 10-year-old child”. DCE data were analyzed using a mixed-logit model. The 243 DCE predicted values were mapped into the observed 28 cTTO values using linear and non-linear mapping approaches with and without intercept. Mapping approaches’ performance was assessed to estimate the most valid method to rescale DCE predicted values using the model ft (R2 ), Akaike Information Criteria (AIC), root mean squared error (RMSE), and mean absolute error (MAE). Results A representative sample of 1376 Brazilian adults participated (DCE, 1152; cTTO, 211). The linear mapping without intercept (R2 = 96%; AIC, − 44; RMSE, 0.0803; MAE, − 0.0479) outperformed the non-linear without intercept (R2 = 98%; AIC, − 63; RMSE, 0.1385; MAE, − 0.1320). Utilities ranged from 1 (full health) to − 0.0059 (the worst health state). High- est weights were assigned to having pain or discomfort (pain/discomfort), followed by walking about (mobility), looking after myself (self-care), doing usual activities (usual activities), and feeling worried, sad, or unhappy (anxiety/depression). Conclusion This study elicited the Brazilian EQ-5D-Y-3L value set using a mixed-logit DCE model with a power parameter based on a linear mapping without intercept, which can be used to estimate the quality-adjusted life-years for economic evaluations of health technologies targeting the Brazilian youth population.en
dc.identifier.citationEspirito Santo CM, Miyamoto GC, Santos VS, Ben ÂJ, Finch AP, Roudijk B, de Jesus-Moraleida FR, Stein AT, Santos M, Yamato TP. Estimating an EQ-5D-Y-3L Value Set for Brazil. Pharmacoeconomics. 2024 Sep;42(9):1047-1063. doi: 10.1007/s40273-024-01404-9.
dc.identifier.otherDOI: 10.1007/s40273-024-01404-9
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/812
dc.language.isoen
dc.publisherPharmacoEconomics
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectBrazilen
dc.subjectChilden
dc.subjectChoice Behavioren
dc.subjectFemaleen
dc.subjectHealth Statusen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectQuality of Life*en
dc.subjectSurveys and Questionnairesen
dc.subjectYoung Adult.en
dc.titleEstimating an EQ‐5D‐Y‐3L Value Set for Brazil
dc.typeArticle
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