Follow-up of a cohort of patients with noncystic fibrosis bronchiectasis for 1 year

Mateus, Simone Paulo
Salles, Raquel Esteves Brandão
Costa, Walter
Costa, Claudia Henrique da
Lopes, Agnaldo José
Tura, Bernardo Rangel
Rufino, Rogério
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Revista da Associação Médica Brasileira
Objective: The objective of this study was to evaluate the quality of life of patients with noncystic fibrosis bronchiectasis during a 1-year follow-up by using the EuroQol - 5 Dimensions - 3 Levels (EQ-5D-3L) questionnaire. Methods: A cohort study was conducted with 100 patients with noncystic fibrosis bronchiectasis and followed up with face-to-face visits or by telephone contact every 3 months for 1 year. All patients were recruited from a single referral center for bronchiectasis. At the time of recruiting and at the end of 1 year, the EQ-5D-3L questionnaire was applied to evaluate the patients' quality of life. Variables, such as exacerbation, emergency care, comorbidities, hemoptysis, colonization, and hospitalization, were assessed. Results: Of the 100 patients, 99 completed the study and 72% were women. There were no marked limitations in the mobility and self-care domains during the follow-up. At the end of the follow-up, 32 patients were extremely anxious or depressed. The quality of life assessed by using EQ-5D-3L had an initial mean score of 0.545 and of 0.589 after 1 year, which was statistically significant (p=0.011). Conclusion: Patients with noncystic fibrosis bronchiectasis have a poor quality of life, and the EQ-5D-3L questionnaire may be a tool for monitoring patients with bronchiectasis.
Mateus SP, Salles REB, Costa W, Costa CHD, Lopes AJ, Tura BR, Rufino R. Follow-up of a cohort of patients with noncystic fibrosis bronchiectasis for 1 year. Rev Assoc Med Bras (1992). 2022 Mar;68(3):329-336. doi: 10.1590/1806-9282.20210710.