Prevalence of potential bacterial respiratory pathogens in the oral cavity of hospitalised individuals

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dc.contributor.authorZuanazzi, David
dc.contributor.authorSouto, Renata
dc.contributor.authorMattos, Marcelo Barbosa Accioly
dc.contributor.authorZuanazzi, Maura Rodrigues
dc.contributor.authorTura, Bernardo Rangel
dc.contributor.authorSansone, Carmelo
dc.contributor.authorColombo, Ana Paula Vieira
dc.date.accessioned2023-12-06T14:22:31Z
dc.date.available2023-12-06T14:22:31Z
dc.date.issued2010
dc.description.abstractObjective: To assess the prevalence of oral colonisation by bacterial respiratory pathogens in hospitalised patients. Methods: Thirty patients undergoing myocardium revascularisation surgery were evalu ated. At baseline (pre-operative phase), full-mouth clinical periodontal assessment was performed. Saliva and biofilm samples were obtained from subjects at baseline and at the post-operative phase, after orotracheal extubation. DNA was extracted from samples and species of Acinetobacter, Pseudomonas, Staphylococcus aureus and Dialister pneumosintes were detected by PCR or culture (for staphylococci isolates). Results: Most of the subjects were males, with history of hypertension and smoking. Thirteen were edentulous (ED) and 17 were dentate (DE), with moderate chronic period ontitis. The most prevalent bacteria in saliva were Staphylococcus spp. (85.7%), Pseudomonas spp. (83.8%), and Acinetobacter spp. (53.3%). There was a trend for D. pneumosintes to be more frequently detected in DE (43.7%) than ED (11.5%) patients. In plaque samples, DE with >14 teeth showed a higher prevalence of Pseudomonas spp. (100%) than individuals with 14 teeth (69.1%; p = 0.048). Conversely, P. aeruginosa was more prevalent in subjects with fewer teeth (35.5%) than with >14 teeth (5.7%; p = 0.037). All staphylococci isolates were coagulase negative, and about 11% were positive for the mecA gene. These mecA-positive isolates showed a tendency to increase in all samples, whereas P. aeruginosa reduced after surgery. A strong correlation between the presence of Acinetobacter spp. and Pseudomonas spp. was observed (rho = 0.886, p < 0.05). Conclusions: The oral cavity of hospitalised patients harbours high frequencies of bacterial respiratory pathogens, supporting its potential role as a reservoir for these species.
dc.identifier.citationZuanazzi D, Souto R, Mattos MB, Zuanazzi MR, Tura BR, Sansone C, Colombo AP. Prevalence of potential bacterial respiratory pathogens in the oral cavity of hospitalised individuals. Arch Oral Biol. 2010 Jan;55(1):21-8. doi: 10.1016/j.archoralbio.2009.10.005. Epub 2009 Nov 24. PMID: 19939349.
dc.identifier.otherDOI: 10.1016/j.archoralbio.2009.10.005
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/371
dc.language.isoen
dc.publisherArchives of Oral Biology
dc.subjectNosocomial infectionsen
dc.subjectPeriodontal diseaseen
dc.subjectSalivaen
dc.subjectDental plaqueen
dc.subjectRespiratory pathogensen
dc.subject.meshStatistics, Nonparametricen
dc.subject.meshStaphylococcus / isolation & purificationen
dc.subject.meshSaliva / microbiologyen
dc.subject.meshPseudomonas / isolation & purificationen
dc.subject.meshPrevalenceen
dc.subject.meshPolymerase Chain Reactionen
dc.subject.meshPeriodontitis / microbiologyen
dc.subject.meshMouth / microbiologyen
dc.subject.meshMiddle Ageden
dc.subject.meshMaleen
dc.subject.meshInpatientsen
dc.subject.meshHumansen
dc.subject.meshFemaleen
dc.subject.meshDental Plaque / microbiologyen
dc.subject.meshCross Infection / microbiologyen
dc.subject.meshCross Infection / epidemiologyen
dc.subject.meshCoronary Disease / surgeryen
dc.subject.meshChi-Square Distributionen
dc.subject.meshBiofilmsen
dc.subject.meshAcinetobacter / isolation & purificationen
dc.titlePrevalence of potential bacterial respiratory pathogens in the oral cavity of hospitalised individuals
dc.typeArticle
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