COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil

Página do item simplificado
dc.contributor.authorPaulino, Mariah Rodrigues
dc.contributor.authorMoreira, José Alfredo de Sousa
dc.contributor.authorCorreia, Marcelo Goulart
dc.contributor.authorSantos, Léo Rodrigo Abrahão dos
dc.contributor.authorDuarte, Ingrid Paiva
dc.contributor.authorSabioni, Letícia Roberto
dc.contributor.authorMucillo, Fabiana Bergamin
dc.contributor.authorGarrido, Rafael Quaresma
dc.contributor.authorPacheco, Stephan Lachtermacher
dc.contributor.authorde Lorenzo, Andrea
dc.contributor.authorLamas, Cristiane da Cruz
dc.date.accessioned2024-10-10T16:56:20Z
dc.date.available2024-10-10T16:56:20Z
dc.date.issued2021
dc.description.abstractBackground: Cardiovascular disease is associated with severe COVID-19. Our aim was to describe clinical and laboratory features (including electrocardiographic and echocardiographic ones) and outcomes of patients with cardiac disease hospitalized with COVID-19. Methods: This is an observational retrospective study of consecutive adult patients admitted, between March and September of 2020, with confirmed SARSCoV-2 infection. Data were collected as per the ISARIC case report form and complemented with variables related to heart disease. Results: One hundred twenty-one patients were included. Mean age was 60 SD 15.2 years and 80/121(66.1%) were male. Two-thirds of the patients (80/121, 66.1%) had COVID-19 at the time of hospital admission and COVID-19 was the reason for hospitalization in 42 (34.7%). Other reasons for hospital admission were acute coronary syndrome (26%) and decompensated heart failure (14.8%). Chronic cardiac diseases were found in 106/121 (87.6%), mostly coronary artery disease (62%) or valve disease (33.9%). A transthoracic echocardio- gram was performed in 93/121(76.8%) and enlarged cardiac chambers were found in 71% (66/93); admission ECG was done in 93 cases (93/121, 76.8%), and 89.2% (83/93) were abnormal. Hospital-acquisition of COVID- 19 occurred in 20 (16.5%) of patients and their mortality was 50%. On bivariate analysis for mortality, BNP levels and troponin levels were NOT associated with mortality. On multivariate analysis, only C reactive protein levels and creatinine levels were significant. Conclusions: COVID-19 impacted the profile of hospital admissions in cardiac patients. BNP and troponin levels were not associated with mortality and may not be good prognostic discriminators in cardiac patients.
dc.identifier.citationPaulino MR, Moreira JAS, Correia MG, Dos Santos LRA, Duarte IP, Sabioni LR, Mucillo FB, Garrido RQ, Pacheco SL, de Lorenzo A, Lamas CDC. COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil. Am Heart J Plus. 2021 Dec;12:100069. doi: 10.1016/j.ahjo.2021.100069.
dc.identifier.otherDOI: 10.1016/j.ahjo.2021.100069
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/483
dc.language.isoen
dc.publisherAmerican Heart Journal Plus : Cardiology Research and Practice
dc.subjectCoronavirusen
dc.subjectCOVID-19en
dc.subjectCardiac diseaseen
dc.subjectCardiac surgeryen
dc.subjectHospitalizationen
dc.subjectMortalityen
dc.titleCOVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil
dc.typeArticle
Arquivos
Original bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.alt
Nome:
Paulino MR et al_AM Heart J Plus.pdf
Tamanho:
427.78 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
License bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.placeholder
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed to upon submission
Descrição:
Baixar
Coleções
Produção Docente