Acute effects of energy drink consumption on microvascular reactivity in young male volunteers at rest: a randomized trial
Acute effects of energy drink consumption on microvascular reactivity in young male volunteers at rest: a randomized trial
Data
2024
Autores
Skaf-Gonçalves, L.
Peçanha, D.
Kasal, D.
Tibiriçá, E.
Journal Title
Journal ISSN
Volume Title
Publisher
Brazilian Journal of Medical and Biological Research
Resumo
Energy drinks are nonalcoholic beverages whose main ingredients are sugar, taurine, and caffeine. The consumption of energy
drinks is increasing worldwide, but only a few conflicting studies have investigated the vascular effects of energy drinks in young
adults. The aim of this study was to evaluate microvascular reactivity before and after energy drinks consumption in young
healthy male volunteers. This was a cross-sectional prospective study. Microvascular reactivity signals were evaluated in the
skin of the forearm using laser speckle contrast imaging with acetylcholine (ACh) iontophoresis before and 90 and 180 min after
the randomized consumption of one ED or the same volume of water (control), followed by a postocclusive reactive hyperemia
(PORH) test. Thirty-two volunteers were evaluated (age: 25.4±4.3 years). Energy drink consumption prevented the rest-
induced reduction in cutaneous vascular conductance over time that was observed in the control group. In the control group,
there were significant reductions in microvascular vasodilation at 90 and 180 min compared to baseline (P=0.004), but this was
not the case in the energy drink group (P=0.76). Our results demonstrated that the reduction in microvascular conductance
associated with prolonged immobility can be prevented by the consumption of one energy drink, highlighting the vasodilator
effects of this beverage in young individuals at rest. The between-study variability in terms of the brand of energy drinks and the
ingested volume, as well as the method of vascular evaluation and the inclusion criteria, may explain the discrepancies among
previous studies on the vascular effects of energy drinks.
Description
Palavras-chave
Endothelial function, Energy drinks, Laser speckle, Microvascular reactivity, Randomized trial.
Citação
Skaf-Gonçalves L, Peçanha D, Kasal D, Tibirica E. Acute effects of energy drink consumption on microvascular reactivity in young male volunteers at rest: a randomized trial. Braz J Med Biol Res. 2024 Aug 23;57:e13624. doi: 10.1590/1414-431X2024e13624.