Accuracy of positron emission tomography and positron emission tomography-CT in the detection of differentiated thyroid cancer recurrence with negative 131I whole-body scan results: A meta-analysis
Accuracy of positron emission tomography and positron emission tomography-CT in the detection of differentiated thyroid cancer recurrence with negative 131I whole-body scan results: A meta-analysis
Data
2016
Autores
Caetano, Rosângela
Bastos, Claudia Regina Garcia
Oliveira, Ione Ayala Gualandi de
Silva, Rondineli Mendes da
Fortes, Clarisse Pereira Dias Drumond
Pepe, Vera Lucia Edais
Reis, Lenice Gnocchi
Braga, Jose Ueleres
Journal Title
Journal ISSN
Volume Title
Publisher
Head & Neck
Resumo
Background. The purpose of this review was to present a
meta-analysis aimed to evaluate the accuracy of positron emission
tomography (PET) and PET-CT for detecting recurrence of differentiated
thyroid carcinoma (DTC) not identified by 131I whole-body scintigraphy.
Methods. MEDLINE, EMBASE, LILACS, and Cochrane databases were
searched for studies published between January 1985 and March 2012.
Systematic methods were used to select and evaluate the quality of
studies. Pooled sensitivity and specificity for conventional PET and PET-
CT was estimated using random effects model.
Results. Twenty studies were included in the systematic review; the data
of 18 studies were used in the meta-analysis. The combined sensitivity
and specificity for conventional PET were both found to be 84%; for PET-
CT, they were 93% and 81%, respectively. The overall accuracies were
91% and 93%, respectively.
Conclusion. 18Fluorodeoxyglucose (FDG)-PET and PET-CT are highly
accurate diagnostics tools for DTC recurrence in patients who present a
negative whole-body scintigraphy and could impact the clinical and ther-
apeutic management of DTC. VC 2015 Wiley Periodicals, Inc. Head Neck
38: 316–327, 2016.
Description
Palavras-chave
thyroid cancer, differentiated thyroid carcinoma, negative radioiodine whole-body scan, 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET),, meta-analysis
Citação
Caetano R, Bastos CR, de Oliveira IA, da Silva RM, Fortes CP, Pepe VL, Reis LG, Braga JU. Accuracy of positron emission tomography and positron emission tomography-CT in the detection of differentiated thyroid cancer recurrence with negative (131) I whole-body scan results: A meta-analysis. Head Neck. 2016 Feb;38(2):316-27. doi: 10.1002/hed.23881.