Impacto orçamentário da diacereína no tratamento da osteoartrite de joelho
Impacto orçamentário da diacereína no tratamento da osteoartrite de joelho
Data
2018
Autores
Oliveira, Cristiane Rocha de
Zimmermann, Ivan Ricardo
Sousa, Eduardo Branco de
Silva, Roberto Carlos Lyra da
Journal Title
Journal ISSN
Volume Title
Publisher
JORNAL DE ASSISTÊNCIA FARMACÊUTICA E FARMACOECONOMIA
Resumo
Objetivos: conhecer os custos e estimar o impacto orçamentário do
Instituto Nacional de Traumatologia e Ortopedia sobre o uso da diacereína
no tratamento medicamentoso oferecido aos pacientes ambulatoriais com
osteoartrite do joelho. Método: foram desenvolvidas etapas para a análise de
impacto orçamentário incremental, descrevendo o cenário de linha de base
e o conjunto de medicamentos já utilizados na instituição; descrevendo o
cenário alternativo com inserção de diacereína e estimando o custo direto da
introdução deste medicamento para a fração de pacientes elegíveis. As es-
timativas serão convertidas em dólares e euros, utilizando a taxa de câmbio
do dia 29 de dezembro de 2017, segundo banco central. Dados públicos
foram consultados a partir do cadastro de compras governamentais e do
sistema informatizado do Instituto. Análise de sensibilidade determinística
e probabilística foi aplicada para verificar o impacto de incertezas e pressu-
postos. O horizonte temporal de cinco anos foi considerado na comparação
dos cenários. A análise foi feita sob a perspectiva dos gestores da instituição.
Resultados: um perfil dos pacientes ambulatoriais com osteoartrites que re-
cebem tratamento no Instituto; medicamentos mais prescritos neste Instituto
e seus custos diretos de aquisição. O impacto orçamentário da diacereína
como terapia adjuvante foi estimado para este cenário. Houve um aumento
de 6% nos custos institucionais de compra de medicamentos. Conclusões: a
análise do impacto orçamentário da diacereína no tratamento da osteoartrite
de joelho permite aos gestores da instituição o planejamento de recursos e
implementação de estratégias para tal tratamento, assim como, elaboração
de um protocolo clínico e diretrizes terapêuticas para esta população específica.
Objectives: to know the costs and estimate the budget impact for the Brazilian Traumatology and Orthopedics Institute regarding the use of diacerein in drug treatment offered to outpatients with knee osteoarthritis. Method: steps for incremental budget impact analysis were developmented describing the baseline scenario and set of medicines has already used in the institution; describing the alternative scenario with insertion of diacerein and estimating the direct cost of this medicine for the fraction of eligible patients. The estimates will be converted into dollars and euros, using the exchange rate of December 29, 2017, according to the central bank. Public data were consulted from the governmental purchase register and the com- puterized system of the Institute. Deterministic and probabilistic sensitivity analysis were applied to check the impact of uncertainties and conjectures. Time horizon of five years was considered when comparing the scenarios. Analysis were made from the perspective of institution manegers. Results: a profile of the outpatients with osteoarthrits that receive treatment at Ins- titute; the most prescribed medicines in this institute and its direct cost of acquisition. The budget impact for the Institute of diacerein as a adjuvant therapy were estimated. There was a increase of 6% in purchase institutio- nal drug costs. Conclusions: the budget impact of diacerein in the treatment of osteoarthritis of the knee allows the managers of the institution to plan on resources and strategies for such treatment, as well as to develop therapeutic guidelines for this specific population.
Objectives: to know the costs and estimate the budget impact for the Brazilian Traumatology and Orthopedics Institute regarding the use of diacerein in drug treatment offered to outpatients with knee osteoarthritis. Method: steps for incremental budget impact analysis were developmented describing the baseline scenario and set of medicines has already used in the institution; describing the alternative scenario with insertion of diacerein and estimating the direct cost of this medicine for the fraction of eligible patients. The estimates will be converted into dollars and euros, using the exchange rate of December 29, 2017, according to the central bank. Public data were consulted from the governmental purchase register and the com- puterized system of the Institute. Deterministic and probabilistic sensitivity analysis were applied to check the impact of uncertainties and conjectures. Time horizon of five years was considered when comparing the scenarios. Analysis were made from the perspective of institution manegers. Results: a profile of the outpatients with osteoarthrits that receive treatment at Ins- titute; the most prescribed medicines in this institute and its direct cost of acquisition. The budget impact for the Institute of diacerein as a adjuvant therapy were estimated. There was a increase of 6% in purchase institutio- nal drug costs. Conclusions: the budget impact of diacerein in the treatment of osteoarthritis of the knee allows the managers of the institution to plan on resources and strategies for such treatment, as well as to develop therapeutic guidelines for this specific population.
Description
Palavras-chave
Análise de impacto orçamentário, Farmacoeconomia, Osteoartrite do joelho;, Custos da doença, Ortopedia, Budget analysis, Pharmaceutical Economics, Knee Osteoarthritis, Cost of Illness, Orthopedics
Citação
Rocha CO, Zimmermann IR, Sousa EB, Lyra RCS. (2022). Impacto orçamentário da Diacereína no tratamento da osteoartrite de joelho. JORNAL DE ASSISTÊNCIA FARMACÊUTICA E FARMACOECONOMIA, 3(3). doi: 10.22563/2525-7323.2018.v3.n3.p.27-36