Prevalência de insegurança alimentar e sua associação com desfechos de saúde e qualidade de vida em pacientes com doença de Chagas crônica
Prevalência de insegurança alimentar e sua associação com desfechos de saúde e qualidade de vida em pacientes com doença de Chagas crônica
Data
2023
Autores
Costa, Celson Júnio do Nascimento
Journal Title
Journal ISSN
Volume Title
Publisher
Instituto Nacional de Cardiologia
Resumo
Introdução: A doença de Chagas (DC) é uma doença negligenciada que afeta 6 a 7 milhões de pessoas em todo o mundo. Indivíduos com DC geralmente possuem baixos níveis socioeconômicos e, portanto, são mais propensos à insegurança alimentar (IA). Objetivo: Avaliar a frequência de IA em pacientes com DC crônica e sua associação com medidas antropométricas, comorbidades, perfil lipídico, glicose e qualidade de vida (QV). Métodos: Este é um estudo transversal que incluiu pacientes adultos com DC crônica. A IA foi avaliada de acordo com a Escala Brasileira de IA (EBIA 2003). As medidas antropométricas incluíram peso, altura e circunferência da cintura. As comorbidades incluíram hipertensão arterial, diabetes mellitus, dislipidemia e obesidade. O perfil lipídico e a glicose plasmática foram avaliados em jejum de 12 horas. A QV foi avaliada usando o questionário WHOQOL-Bref. As estatísticas descritivas foram realizadas para variáveis categóricas. Foram utilizados modelos de regressão linear e logística ajustados para idade, sexo, escolaridade, raça e forma cardíaca/digestiva para avaliar a associação entre o status de IA e medidas antropométricas, comorbidades e biomarcadores. Modelo de regressão linear ajustado para idade, sexo, raça, escolaridade, comorbidades e forma cardíaca/digestiva de DC foi usado para avaliar a associação entre o status de IA e a QV. Resultados: Dos 359 participantes incluídos (55,9% mulheres, mediana de idade 62 anos), 22,7% apresentavam IA leve e 8% apresentavam IA moderada/grave. Nos modelos ajustados, a IA leve foi significativamente associada à obesidade (OR=1,83; IC 95%=1,03 a 3,25). Foram observadas associações significativas entre IA e todos os domínios da QV, incluindo saúde física (IA leve: β= -8,37; IC 95% -12,32 a -4,43; IA moderada/grave: β= -7,99; IC 95% -14,09 a -1,89), domínio psicológico (IA leve: β= -5,42; IC 95% -8,99 a -1,85; IA moderada/grave: β= -7,09; IC 95% -12,62 a -1,57), domínio de relacionamentos sociais (IA leve: β= -6,64; IC 95% -10,40 a -2,88), domínio do ambiente (IA leve: β= -8,85; IC 95% -12,04 a -5,65; IA moderada/grave: β= -13,66; IC 95% -18,61 a -8,71) e domínio geral (IA leve: β= -8,07; IC 95% -12,12 a -4,01; IA moderada/grave: β= -16,73; IC 95% -23,00 a -10,46). Esses achados sugerem que a IA está consistentemente associada a uma pior QV em pacientes com DC crônica e destacam a necessidade de intervenções para abordar esse problema nos serviços de saúde. Palavras-chave: Doença de Chagas, Insegurança Alimentar, Medidas Antropométricas, Qualidade de Vida, Prevalência.
Introduction: Chagas disease (CD) is a neglected disease that affects 6 to 7 million people worldwide. Individuals with CD often have low socioeconomic levels and are therefore more susceptible to food insecurity (FI). Objective: To evaluate the frequency of FI in patients with chronic CD and its association with anthropometric measures, comorbidities, lipid profile, glucose, and quality of life (QOL). Methods: This is a cross-sectional study that included patients with chronic CD of both sexes. FI was assessed according to the Brazilian Food Insecurity Scale (EBIA 2003). Anthropometric measures included weight, height, and waist circumference. Comorbidities included arterial hypertension, diabetes mellitus, dyslipidemia, and obesity. Lipid profile and plasma glucose were assessed after a 12-hour fast. QOL was evaluated using the WHOQOL-Bref questionnaire. Descriptive statistics included median (interquartile range from 25% to 75%) and percentage (frequency) for categorical variables. Linear and logistic regression models adjusted for age, sex, education, race, and cardiac/digestive form were used to evaluate the association between FI status and anthropometric measures, comorbidities, and biomarkers. A linear regression model adjusted for age, sex, race, education, comorbidities, and cardiac/digestive form of CD was used to assess the association between FI status and QOL. Results: Of the 359 participants included (55.9% women, median age 62 years), 22.7% had mild FI and 8% had moderate/severe FI. In adjusted models, mild FI was significantly associated with obesity (OR=1.83; 95% CI=1.03 to 3.25). Significant associations were observed between FI and all domains of QOL, including physical health (mild FI: β= -8.37; 95% CI -12.32 to -4.43; moderate/severe FI: β= -7.99; 95% CI -14.09 to -1.89), psychological domain (mild FI: β= -5.42; 95% CI -8.99 to -1.85; moderate/severe FI: β= -7.09; 95% CI -12.62 to -1.57), social relationships domain (mild FI: β= -6.64; 95% CI -10.40 to -2.88), environment domain (mild FI: β= -8.85; 95% CI -12.04 to -5.65; moderate/severe FI: β= -13.66; 95% CI -18.61 to -8.71), and overall domain (mild FI: β= -8.07; 95% CI -12.12 to -4.01; moderate/severe FI: β= -16.73; 95% CI -23.00 to -10.46). These findings suggest that FI is consistently associated with poorer QOL in patients with chronic CD and emphasize the need for interventions to address this issue in healthcare services. Keywords: Chagas Disease, Food Insecurity, Anthropometric Measures, Quality of Life, Prevalence.
Introduction: Chagas disease (CD) is a neglected disease that affects 6 to 7 million people worldwide. Individuals with CD often have low socioeconomic levels and are therefore more susceptible to food insecurity (FI). Objective: To evaluate the frequency of FI in patients with chronic CD and its association with anthropometric measures, comorbidities, lipid profile, glucose, and quality of life (QOL). Methods: This is a cross-sectional study that included patients with chronic CD of both sexes. FI was assessed according to the Brazilian Food Insecurity Scale (EBIA 2003). Anthropometric measures included weight, height, and waist circumference. Comorbidities included arterial hypertension, diabetes mellitus, dyslipidemia, and obesity. Lipid profile and plasma glucose were assessed after a 12-hour fast. QOL was evaluated using the WHOQOL-Bref questionnaire. Descriptive statistics included median (interquartile range from 25% to 75%) and percentage (frequency) for categorical variables. Linear and logistic regression models adjusted for age, sex, education, race, and cardiac/digestive form were used to evaluate the association between FI status and anthropometric measures, comorbidities, and biomarkers. A linear regression model adjusted for age, sex, race, education, comorbidities, and cardiac/digestive form of CD was used to assess the association between FI status and QOL. Results: Of the 359 participants included (55.9% women, median age 62 years), 22.7% had mild FI and 8% had moderate/severe FI. In adjusted models, mild FI was significantly associated with obesity (OR=1.83; 95% CI=1.03 to 3.25). Significant associations were observed between FI and all domains of QOL, including physical health (mild FI: β= -8.37; 95% CI -12.32 to -4.43; moderate/severe FI: β= -7.99; 95% CI -14.09 to -1.89), psychological domain (mild FI: β= -5.42; 95% CI -8.99 to -1.85; moderate/severe FI: β= -7.09; 95% CI -12.62 to -1.57), social relationships domain (mild FI: β= -6.64; 95% CI -10.40 to -2.88), environment domain (mild FI: β= -8.85; 95% CI -12.04 to -5.65; moderate/severe FI: β= -13.66; 95% CI -18.61 to -8.71), and overall domain (mild FI: β= -8.07; 95% CI -12.12 to -4.01; moderate/severe FI: β= -16.73; 95% CI -23.00 to -10.46). These findings suggest that FI is consistently associated with poorer QOL in patients with chronic CD and emphasize the need for interventions to address this issue in healthcare services. Keywords: Chagas Disease, Food Insecurity, Anthropometric Measures, Quality of Life, Prevalence.
Description
Palavras-chave
Doença de Chagas, Insegurança Alimentar, Medidas Antropométricas, Qualidade de Vida, Prevalência, Chagas Disease, Food Insecurity, Anthropometric Measures, Quality of Life, Prevalence
Citação
Costa CJN. Prevalência de insegurança alimentar e sua associação com desfechos de saúde e qualidade de vida em pacientes com doença de Chagas crônica. Dissertação [Mestrado Profissional em Ciências Cardiovasculares] - Instituto Nacional de Cardiologia; 2022.