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    Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
    (BMC Research Notes, 2018) Evangelista, Maria do Socorro Nantua; Maia, Rosalia; Toledo, João Paulo; Abreu, Ricardo Gadelha de; Braga, José Uereles; Barreira, Draurio; Trajman, Anete
    Objective: The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil. Results: Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR=2.06; 1.97–2.16).