PCN163 Developing attributes and attribute-levels for a discrete choice experiment on lung cancer patient’s preferences for drug therapies

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Data
2017
Autores
Monteiro, Andrea Libório
Santos, Marisa
Fontes, LS
Journal Title
Journal ISSN
Volume Title
Publisher
Value in Health
Resumo
OBJECTIVES: Stated preferences experiments validity depends largely on the proper specifications of attributes and levels. Hence, patients and physicians engagement is critical to assure that the information being valued on the experiment is both important to patients and decision-relevant. This study reports the systematic approach undertaken targeting the definition of attributes and attribute levels for a discrete choice experiment created to elicit lung cancer patient’s preferences for drug therapies. METHODS: A literature review was undertaken aiming to identify conceptual attributes and attribute-levels. The finding of this review helped to define the qualitative component. The qualitative component included 3 focus groups, on which 8 patients and 3 oncologists were engaged on discussions aiming to identify context specific attributes. All inter- views were recorded, transcribed and analyzed by the research team. The resulting draft-proposal of attributes and attribute-levels was thoroughly dis- cussed and further developed by a group of experts. RESULTS: The first round of results derived 10 attributes. Attribute-levels were defined according with the literature, the results from the qualitative component and experts opinions. After a round of discussion with experts on the field three attributes were discarded. The final proposal consists in seven attributes that were defined as follows: Fatigue/tiredness, diarrhea, skin rash, risk of hospitalization, mode of adminis- tration (route of drugs administration), access and overall survival. CONCLUSIONS: The results reported in this manuscript will add to the body of knowledge on the application of qualitative methods to derive attributes and attribute-levels for a stated preferences experiment.
Description
Palavras-chave
Lung neoplasms, Drug therapy, Brazil, Discrete choice of experiment
Citação
Monteiro AL, Santos M, Fontes LS. PCN163 Developing attributes and attribute-levels for a discrete choice experiment on lung cancer patient’s preferences for drug therapies. Value Health. 2017;20:A116.