Systemic microvascular dysfunction in COVID-19

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dc.contributor.authorSabioni, Leticia R
dc.contributor.authorTibirica, Eduardo
dc.contributor.authorLamas, Cristiane C.
dc.contributor.authorAmorim, Guilherme D.
dc.contributor.authorLorenzo, Andrea De
dc.date.accessioned2022-09-14T12:51:50Z
dc.date.available2022-09-14T12:51:50Z
dc.date.issued2020
dc.description.abstractCOVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while having lung injury as its most prominent feature, has been increasingly shown to affect endothelial cell function and the microvasculature. In this report, a woman with COVID-19, cardiac valve disease and spherocytosis was assessed with laser Doppler perfusion monitoring. Systemic microvascular reactivity was impaired during a worsening phase of COVID-19, but improved after clinical recovery; microcirculatory dysfunction paralleled systemic inflammation and pulmonary involvement. The assessment of systemic microcirculatory function may therefore provide insights on COVID-19 pathophysiology.en
dc.identifier.citationSabioni LR, Tibirica E, Lamas CC, Amorim GD, Lorenzo AD. Systemic microvascular dysfunction in COVID-19. Am J Cardiovasc Dis. 2020; 10(4): 386–391.
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/269
dc.language.isoen
dc.publisherAmerican Journal of Cardiovascular Disease
dc.subjectCOVID-19en
dc.subjectLaser Doppler perfusion imagingen
dc.subjectEndothelial dysfunctionen
dc.subjectMicrovascular reactivityen
dc.subjectCardiac valve diseaseen
dc.titleSystemic microvascular dysfunction in COVID-19en
dc.typeArticleen
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