The Role of Strain in the Prognosis of Transthyretin Amyloidosis

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dc.contributor.authorSilva, Ana Karolina Bento Bento da
dc.contributor.authorCavalcanti, Leonardo Torreão Bezerra
dc.contributor.authorBarberato, Silvio Henrique
dc.contributor.authorFelix, Alex dos Santos
dc.contributor.authorMelo, Marcelo Dantas Tavares de
dc.date.accessioned2025-01-29T12:09:26Z
dc.date.available2025-01-29T12:09:26Z
dc.date.issued2024
dc.description.abstractTransthyretin amyloidosis (TTRA) is a systemic infiltrative disease where cardiac involvement is paramount for prognosis. The strain technique plays a crucial role in non-invasive cardiac screening for this condition. Research on the prognostic utility of cardiac deformation in TTRA indicates the significance of right ventricular (RV) free wall strain, global longitudinal strain (GLS), left and right atrium reservoir strain, in descending order of publication, respectively. The GLS has emerged as a promising tool for therapeutic monitoring. Analyzing myocardial deformation is vital due to its incremental value over other clinical, laboratory, and imaging parameters. However, caution is warranted due to limited data on its prognostic and therapeutic monitoring use in TTRA. Despite the strong rationale for employing myocardial deformation in patient stratification, further robust studies are necessary to establish it as a new prognostic marker in TTRA.
dc.identifier.citationSilva AKBB, Cavalcanti LTB, Barberato SH, Felix AS, Melo MDT. The Role of Strain in the Prognosis of Transthyretin Amyloidosis. Int J Cardiovasc Sci 2024;37:e20240082. doi: 10.36660/ijcs.20240082.
dc.identifier.otherDOI: 10.36660/ijcs.20240082
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/763
dc.language.isoen
dc.publisherInternational Journal of Cardiovascular Sciences
dc.subjectEchocardiographyen
dc.subjectCardiomyopathiesen
dc.subjectHeart Failure.en
dc.titleThe Role of Strain in the Prognosis of Transthyretin Amyloidosis
dc.typeArticle
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