Associação entre dispneia e qualidade de vida em trabalhadores de um hospital quaternário que tiveram covid-19
Associação entre dispneia e qualidade de vida em trabalhadores de um hospital quaternário que tiveram covid-19
Data
2024
Autores
Macedo Junior, Humberto Batista de
Journal Title
Journal ISSN
Volume Title
Publisher
Instituto Nacional de Cardiologia
Resumo
Introdução: A pandemia causada pelo novo coronavírus (COVID-19) trouxe um desafio de proporções históricas para os sistemas mundiais de saúde. O Instituto Nacional de Cardiologia (INC) proporcionou o diagnóstico molecular da infecção pelo Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) em funcionários com síndrome gripal. Objetivo: avaliar a evolução clínica e a qualidade de vida em saúde de funcionários do INC com diagnóstico molecular de COVID-19 após a recuperação da fase aguda da doença. Métodos: trata-se de um estudo transversal que incluiu funcionários do INC com diagnóstico molecular positivo para COVID-19. O participante era avaliado em relação a presença de sintomas cardiovasculares e variáveis clínicas, sendo em seguida aplicado o questionário de qualidade de vida em saúde (QVRS) EuroQol (EQ-5D-3L), com a escala visual analógica (EVA). Os dados foram estratificados em indivíduos com e sem queixas de dispneia no momento da avaliação. As associações entre a presença de dispneia com os domínios da QV foram avaliadas por meio de modelos lineares generalizados utilizando log link e distribuição gama para as variáveis de desfecho contínuas e modelos de regressão logística para as variáveis de desfecho binária. Resultados: foram considerados 109 profissionais com diagnóstico positivo para COVID-19, em sua maioria mulheres (67,9%) com mediana de idade de 44(IIQ 25-75% 38-52) anos. A mediana do número de dias entre o diagnóstico e a avaliação clínica foi de 400. Dispneia foi observada em 20,2% (n=22) dos participantes. Não houve diferença entre os grupos com e sem dispneia em relação ao sexo, etnia, categoria de trabalho, status vacinal ou comorbidade. O grupo com dispneia apresentou índice de massa corporal mais elevado(p=0,04). Na análise de regressão, a presença de dispneia esteve associada a menor pontuação na EVA, tanto nos modelos ajustado e não-ajustado. Em acréscimo, dispneia esteve associada com mais relatos de problemas nas atividades habituais do questionário EQ-5D-3L. Pode-se concluir que a presença de dispneia esteve relacionada à piora da QVRS. Estudos adicionais, com períodos de avaliação maiores e com a realização de exames complementares, poderão auxiliar a elucidar os efeitos a longo prazo da COVID-19.
Introduction: The pandemic caused by the new coronavirus (COVID-19) has brought a challenge of historic proportions to global health systems. The National Institute of Cardiology (INC) provided the molecular diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in professionals with flu-like syndrome. Objective: to evaluate the clinical evolution and health quality of life of INC workers with a molecular diagnosis of COVID-19 after recovery from the acute phase of the disease. Methods: This is a cross-sectional analytical that included INC workers who tested positive to COVID-19. The participant was asked to inform cardiovascular complaints and clinical variables and then administered a health-related quality-of-life questionnaire (HRQoL), EuroQol 5-dimensions 3-levels (EQ-5D-3L), with the visual analogue scale (VAS). Data were stratified between individuals with and without complaints of dyspnea at the time of assessment. The relation between dyspnea and the domains of quality of life were evaluated by linear models generalized using log link and gamma distribution to the variables of continuous outcomes and models of logistic regression to the variable of binary outcome. Results: 109 professionals were evaluated, with diagnosis of COVID-19, mostly women (67.9%), with median age of 44 (IIQ 25-75% 38-52) years. The median number of days between diagnosis and clinical evaluation was 400. Dyspnea was observed in 20.2% (n =22) of participants. There was no difference between the groups with and without dyspnea in relation to sex, ethnicity, work category, vaccination status or comorbidity. The group with dyspnea had a higher body mass index (p=0.04). In the regression analysis, the presence of dyspnea was associated with lower VAS scores, both in the adjusted and unadjusted models. In addition, dyspnea was associated with more reports of problems in usual activities in EQ-5D-3L. This study presents possible long-term effects of the disease based on the relationship between the individual perception of dyspnea in daily activities and lower HRQoL. We can conclude that the presence of dyspnea was associated with worsen of quality of life related to health. Additional studies, with longer evaluation periods and carrying out additional exams, may help to elucidate the long-term effects of COVID-19.
Introduction: The pandemic caused by the new coronavirus (COVID-19) has brought a challenge of historic proportions to global health systems. The National Institute of Cardiology (INC) provided the molecular diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in professionals with flu-like syndrome. Objective: to evaluate the clinical evolution and health quality of life of INC workers with a molecular diagnosis of COVID-19 after recovery from the acute phase of the disease. Methods: This is a cross-sectional analytical that included INC workers who tested positive to COVID-19. The participant was asked to inform cardiovascular complaints and clinical variables and then administered a health-related quality-of-life questionnaire (HRQoL), EuroQol 5-dimensions 3-levels (EQ-5D-3L), with the visual analogue scale (VAS). Data were stratified between individuals with and without complaints of dyspnea at the time of assessment. The relation between dyspnea and the domains of quality of life were evaluated by linear models generalized using log link and gamma distribution to the variables of continuous outcomes and models of logistic regression to the variable of binary outcome. Results: 109 professionals were evaluated, with diagnosis of COVID-19, mostly women (67.9%), with median age of 44 (IIQ 25-75% 38-52) years. The median number of days between diagnosis and clinical evaluation was 400. Dyspnea was observed in 20.2% (n =22) of participants. There was no difference between the groups with and without dyspnea in relation to sex, ethnicity, work category, vaccination status or comorbidity. The group with dyspnea had a higher body mass index (p=0.04). In the regression analysis, the presence of dyspnea was associated with lower VAS scores, both in the adjusted and unadjusted models. In addition, dyspnea was associated with more reports of problems in usual activities in EQ-5D-3L. This study presents possible long-term effects of the disease based on the relationship between the individual perception of dyspnea in daily activities and lower HRQoL. We can conclude that the presence of dyspnea was associated with worsen of quality of life related to health. Additional studies, with longer evaluation periods and carrying out additional exams, may help to elucidate the long-term effects of COVID-19.
Description
Palavras-chave
Dispneia, Qualidade de Vida, COVID-19, Profissionais de Saúde, Dyspnea, Quality of life, COVID-19, Health workers
Citação
Macedo Junior HB. Associação entre dispneia e qualidade de vida em trabalhadores de um hospital quaternário que tiveram covid-19. Rio de Janeiro. dissertação [Mestrado Profiossional em Ciências Cardiovasculares] Instituto Nacional de Cardiologia - INC; 2024.