A public health approach to increase treatment of latent TB among household contacts in Brazil

Página do item simplificado
dc.contributor.authorBastos, M. L.
dc.contributor.authorOxlade, O.
dc.contributor.authorBenedetti, A.
dc.contributor.authorFregonese, F.
dc.contributor.authorValiquette, C.
dc.contributor.authorLira, S. C. C.
dc.contributor.authorCarvalho-Cordeiro, D.
dc.contributor.authorCavalcante, J. R.
dc.contributor.authorFaerstein, E.
dc.contributor.authorTrajman, A.
dc.date.accessioned2024-12-10T17:48:34Z
dc.date.available2024-12-10T17:48:34Z
dc.date.issued2020
dc.description.abstractSETTING: Two consecutive trials were conducted to evaluate the effectiveness of a public health approach to identify and correct problems in the care cascade for household contacts (HHCs) of TB patients in three Brazilian high TB incidence cities. METHODS: In the first trial, 12 clinics underwent standardised evaluation using questionnaires admin- istered to TB patients, HHCs and healthcare workers, and analysis of the cascade of latent TB care among HHCs. Six clinics were then randomised to receive interventions to strengthen management of latent TB infection (LTBI), including in-service training pro- vided by nurses, work process organisation and additional clinic-specific solutions. In the second trial, a similar but streamlined evaluation was conducted in two clinics, who then received initial and subsequent intensive in-service training provided by a physician. RESULTS: In the evaluation phase of both trials, many HHCs were identified, but few started LTBI treatment. After the intervention, the number of HHCs initiating treatment per 100 active TB patients increased by 10 (95%CI 11 to 30) in the first trial, and by 44 (95%CI 26 to 61) in the second trial. DISCUSSION: A public health approach with standard- ised evaluation, local decisions for improvements, followed by intensive initial and in-service training appears promising for improved LTBI management.
dc.identifier.citationBastos ML, Oxlade O, Benedetti A, Fregonese F, Valiquette C, Lira SCC, Carvalho-Cordeiro D, Cavalcante JR, Faerstein E, Albuquerque MFM, Cordeiro-Santos M, Hill PC, Menzies D, Trajman A. A public health approach to increase treatment of latent TB among household contacts in Brazil. Int J Tuberc Lung Dis. 2020 Oct 1;24(10):1000-1008. doi: 10.5588/ijtld.19.0728.
dc.identifier.otherDOI: 10.5588/ijtld.19.0728
dc.identifier.urihttps://dspace.inc.saude.gov.br/handle/123456789/691
dc.language.isoen
dc.publisherInternational Journal of Tuberculosis and Lung Disease
dc.subjectcascade of careen
dc.subjectlatent tuberculosis infectionen
dc.subjectimplementationen
dc.subjectpublic health.en
dc.titleA public health approach to increase treatment of latent TB among household contacts in Brazil
dc.typeArticle
Arquivos
Original bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.alt
Nome:
Bastos ML et al_INT J TUBERC LUNG DIS.pdf
Tamanho:
84.98 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
License bundle
Agora exibindo 1 - 1 de 1
thumbnail.default.placeholder
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed to upon submission
Descrição:
Baixar
Coleções
Produção Docente