Tuberculosis among correctional facility workers: A systematic review and meta- analysis
Tuberculosis among correctional facility workers: A systematic review and meta- analysis
Data
2018
Autores
Grenzel, Micheli Luize
Grande, Antonio José
Paniago, Anamaria Mello Miranda
Pompilio, Mauricio Antonio
Oliveira, Sandra Maria do Valle Leone de
Trajman, Anete
Journal Title
Journal ISSN
Volume Title
Publisher
PLOS ONE
Resumo
Introduction
Prison inmates can transmit tuberculosis, including drug-resistant strains, to correctional
facility workers and the community. In this systematic literature review, we investigated the
magnitude of active and latent tuberculosis infection (LTBI) and associated risk factors
among correctional facility workers.
Methods
We searched MEDLINE, EMBASE, LILACS, Cochrane CENTRAL, ISI Web of Science,
CINAHL, and SCOPUS databases (January 1, 1989–December 31, 2017) for studies with
the MeSH terms “prison” (and similar) AND “tuberculosis”, without language restriction. We
searched for gray literature in Google Scholar and conference proceedings. Stratified analy-
ses according to tuberculosis burden were performed.
Results
Of the 974 titles identified, 15 (nine good, six fair quality) fulfilled the inclusion criteria
(110,393 correctional facility workers; six countries; 82,668 active tuberculosis; 110,192
LTBI). Pooled LTBI prevalence and incidence rates were 26% (12–42, I
2 = 99.0%) and 2%
(1–3, I
2 = 98.6%), respectively. LTBI prevalence reached 44% (12–79, I
2 = 99.0%) in high-
burden countries. Active tuberculosis was reported only in low-burden countries (incidence
range, 0.61–450/10,000 correctional facility workers/year). LTBI-associated risk factors
included job duration, older age, country of birth, current tobacco smoking, reported contact
with prisoners, and BCG vaccination.
Conclusion
Despite the risk of bias and high heterogeneity, LTBI was found to be prevalent in correc-
tional facility workers, mainly in high-burden countries. LTBI risk factors suggest both occu-
pational and community exposure. Active tuberculosis occurrence in low-burden countries
suggests higher vulnerability from recent infection among correctional facility workers in
these countries. Systematic surveillance and infection control measures are necessary to
protect these highly vulnerable workers.
Description
Palavras-chave
Female, Humans, atent Tuberculosis* / epidemiology, Latent Tuberculosis* / transmission, Male, Occupational Exposure / adverse effects*, Prevalence, Prisons*, Risk Factors, Tuberculosis, Multidrug-Resistant* / epidemiology, Tuberculosis, Multidrug-Resistant* / transmission.
Citação
Grenzel ML, Grande AJ, Paniago AMM, Pompilio MA, de Oliveira SMVL, Trajman A. Tuberculosis among correctional facility workers: A systematic review and meta-analysis. PLoS One. 2018 Nov 15;13(11):e0207400. doi: 10.1371/journal.pone.0207400.