Direct costs associated to miningococcal disease and related sequelae in children ? analysis based on the braszilian public health system perspective
Direct costs associated to miningococcal disease and related sequelae in children ? analysis based on the braszilian public health system perspective
Data
2016
Autores
Salgado, JB
Silva, DO
Lorenzato, F
Cintra, OA
Saturnino, LT
Journal Title
Journal ISSN
Volume Title
Publisher
Value in Health
Resumo
Objectives to estimate the direct medical costs, under the Brazilian Public Health System (SUS) perspective, associated to invasive meningococcal disease (IMD) in 0-to-1-year-old children and the related main sequelae tracked until they turned 18 years old. Methods a cost-of-illness study was conducted to estimate the SUS expenditure with treatment of IMD acute stage (diagnosis, inpatient treatment and chemoprophylaxis for contacts). During the period of 2007 to 2015, a total of 2,651 notified cases of 0-to-1-year-old children in Brazil were considered. The costs related to the sequelae treatment tracked until they turned 18 years old were calculated using the procedures packages based on the sequelae management recommended by SUS. The assumed sequelae frequency was 23.9% for the occurrence of at least one sequel, the most common being deafness (28%), epilepsy (28%), amputation (9%) and skin necrosis (9%). Brazilian public databases were used to identify the procedures and medications costs. Results the estimated SUS expenditure on acute stage treatment of IMD was USD 456 per patient (1USD = 3.63BRL, March-May 2016), reaching USD 1.1 million for cases in the period of 2007 to 2015. The expenditure related to the main sequelae treatment in the following 17 years was USD 2.1 million, 66% of this value being related to deafness, followed by 20% to amputation, 12% to epilepsy and 2% to skin necrosis. Conclusions the increase of healthcare expenditures reinforces the considerable economic impact of IMD. It is worth emphasizing that the direct costs in this study were estimated in a conservative approach, representing the minimal expenditures associated to IMD in Brazil. It is important to mention that direct medical costs represent only a part of IMD-associated costs. There is a need to conduct other studies that also estimate the indirect costs.
Description
Palavras-chave
Infecções Meningocócicas, Meningococcal Infections, Cost, Custos, Saúde pública, Public health, Sistema Único de Saúde - SUS
Citação
Salgado JB, Silva DO, Lorenzato F, Cintra OA, Saturnino LT. Direct costs associated to miningococcal disease and related sequelae in children ? analysis based on the braszilian public health system perspective. Value in Health. 2016;19(7):PA422. Doi: 10.1016/j.jval.2016.09.438.