Artigos Mestrado CC

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Navegando Artigos Mestrado CC por Assunto "Aged, 80 and over"

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    The association of selenium status with thyroid hormones and anthropometric values in dyslipidemic patients
    (Nutrición Hospitalaria, 2015) Carvalho, Roberta F; Rosa, Glorimar; Huguenin, Grazielle VB; Luiz, Ronir R; Moreira, Annie SB; Oliveira, Glaucia MM
    Background: Selenium (Se) is an essential micronu- trient that performs physiological functions in the meta- bolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascu- lar disease. Aim: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients.Methods: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropo- metric measurements were taken, and dietary Se intake was investigated. Results: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 μg/L. Patients with plasma Se ≥ 95 μg/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m2 , P = 0.02) and waist-to-height ratio (0.65 ± 0.05 vs 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 μg/L. Se intake associated positively with T3 L/T4 L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). Conclusion: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we in- vestigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positi- ve association between Se intake and the most metaboli- cally active form of the thyroid hormones.