Age influences outcomes in 70-year or older patients undergoing isolated coronary artery bypass graft surgery
Age influences outcomes in 70-year or older patients undergoing isolated coronary artery bypass graft surgery
dc.contributor.author | Rocha, Antônio Sergio C. da | |
dc.contributor.author | Pittella, Felipe | |
dc.contributor.author | De Lorenzo, Andrea | |
dc.contributor.author | Barzan, Valmir | |
dc.contributor.author | Colafranceschi, Alexandre Siciliano | |
dc.contributor.author | Brito, José Oscar R. | |
dc.contributor.author | Mattos, Marco Antonio de | |
dc.contributor.author | Silva, Paulo Roberto Dutra da | |
dc.date.accessioned | 2022-09-14T14:31:41Z | |
dc.date.available | 2022-09-14T14:31:41Z | |
dc.date.issued | 2012 | |
dc.description.abstract | Objetivo: Analisar os resultados da cirurgia de revascularização miocárdica (CRVM) isolada com circulação extracorpórea em pacientes com idade ³ 70 anos em comparação àqueles com < 70 anos. Métodos: Pacientes submetidos consecutivamente à CRVM isolada. Os pacientes foram agrupados em G1 (idade³ 70 anos) e G2 (idade < 70 anos). Os desfechos analisados foram letalidade hospitalar, infarto agudo miocárdio (IAM), acidente vascular encefálico (AVE), reoperação para revisão de hemostasia (RRH), necessidade de balão intra-aórtico (BIA), complicações respiratórias, insuficiência renal aguda (IRA), mediastinite, sepse, fibrilação atrial (FA) e bloqueio atrioventricular total (BAVT). Resultados: Foram estudados 1033 pacientes, 257 (24,8%) do G1 e 776 (75,2%) do G2. A letalidade hospitalar foi significantemente maior no G1 quando comparado ao G2 (8,9% vs. 3,6%, P=0,001), enquanto a incidência de IAM foi semelhante (5,8% vs. 5,5%; P=0,87). Maior número de pacientes do G1 necessitou de RRH (12,1% vs. 6,1%; P=0,003). Da mesma forma, no G1 houve maior incidência de complicações respiratórias (21,4% vs. 9,1%; P<0,001), mediastinite (5,1% vs. 1,9%; P=0,013), AVE (3,9% vs. 1,3%; P=0,016), IRA (7,8% vs. 1,3%, P<0,001), sepse (3,9% vs. 1,9%; P=0,003), fibrilação atrial (15,6% vs. 9,8%; P=0,016) e BAVT (3,5% vs. 1,2%; P=0,023) do que o G2. Não houve diferença significante na necessidade de BIA. Na análise regressão logística multivariada “forward stepwise”, a idade ³ 70 anos foi fator preditivo independente para maior. | pt |
dc.description.abstract | Objective: To analyze the results of isolated on-pump coronary artery bypass graft surgery (CABG) in patients ≥ 70 years-old in comparison to patients <70 years-old. Methods: Patients undergoing isolated CABG were selected for the study. The patients were grouped in G1 (age ≥ 70 years-old) and G2 (age <70 years-old). The endpoints were in-hospital mortality, acute myocardial infarction (AMI), stroke, reexploration for bleeding, intra-aortic balloon for circulatory shock, respiratory complications, acute renal failure, mediastinitis, sepsis, atrial fibrillation, and complete atrioventricular block (CAVB). Results: 1,033 patients were included, 257 (24.8%) in G1 and 776 (75.2%) in G2. Patients in G1 were more likely to have in-hospital mortality than G2 (8.9% vs. 3.6%, respectively; P=0.001), while the incidence of AMI was similar (5.8% vs. 5.5%; P=0.87) than G2. More patients in G1 had re-exploration for bleeding (12.1% vs. 6.1%; P=0.003). G1 had more incidence of respiratory complications (21.4% vs. 9.1%; P<0.001), mediastinitis (5.1% vs. 1.9%; P=0.013), stroke (3.9% vs. 1.3%; P=0.016), acute renal failure (7.8% vs. 1.3%; P<0.001), sepsis (3.9% vs. 1.9%;P=0.003), atrial fibrillation (15.6% vs. 9.8%; P=0.016), and CAVB (3.5% vs. 1.2%; P=0.023) than G2. There was no significant difference in the use of intra-aortic balloon. In the forward stepwise multivariate logistic regression analysis age ≥ 70-year-old was an independent predictive factor for higher in-hospital mortality (P=0.004), reexploration for bleeding (P=0.002), sepsis (P=0.002), respiratory complications (P<0.001), mediastinitis (P=0.016), stroke (P=0.029), acute renal failure (P<0.001), atrial fibrillation (P=0.021) and CAVB (P=0.031). Conclusion: This study suggests that patients ≥ 70 yearsold were at increased risk of death and other complications in the CABG’s postoperative period in comparison to younger patients. | en |
dc.identifier.citation | Rocha ASC, Pitella F, De Lorenzo A, Brazan V, Colafranceschi AS, Brito JOR, et al. A idade influencia os desfechos em pacientes com idade igual ou superior a 70 anos submetidos à cirurgia de revascularização miocárdica isolada. Rev Bras Cir Cardiovasc. 2012;27(1):45-51. | |
dc.identifier.uri | https://dspace.inc.saude.gov.br/handle/123456789/276 | |
dc.language.iso | en | |
dc.publisher | Revista Brasileira de Cirurgia Cardiovascular | |
dc.subject | Revascularização miocárdica | pt |
dc.subject | Mortalidade hospitalar | pt |
dc.subject | Complicações pós-operatórias | pt |
dc.subject | Idoso | pt |
dc.subject | Myocardial revascularization | en |
dc.subject | Hospital mortality | en |
dc.subject | Postoperative complications | en |
dc.subject | Aged | en |
dc.subject.mesh | Treatment Outcome | en |
dc.subject.mesh | Reoperation / statistics & numerical data | en |
dc.subject.mesh | Postoperative Complications / epidemiology | en |
dc.subject.mesh | Postoperative Complications / classification | en |
dc.subject.mesh | Middle Aged | en |
dc.subject.mesh | Male | en |
dc.subject.mesh | Humans | en |
dc.subject.mesh | Hospital Mortality | en |
dc.subject.mesh | Female | en |
dc.subject.mesh | Epidemiologic Methods | en |
dc.subject.mesh | Coronary Artery Bypass / mortality | en |
dc.subject.mesh | Coronary Artery Bypass / adverse effects | en |
dc.subject.mesh | Aged | en |
dc.subject.mesh | Age Factors | en |
dc.title | Age influences outcomes in 70-year or older patients undergoing isolated coronary artery bypass graft surgery | en |
dc.title.alternative | A idade influencia os desfechos em pacientes com idade igual ou superior a 70 anos submetidos à cirurgia de revascularização miocárdica isolada | pt |
dc.type | Article |
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