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- ItemAcute cardiac injury in patients with covid-19(American Journal of Cardiovascular Disease, 2020) Lorenzo, Andrea De; Kasal, Daniel Barata; Tura, Bernardo Rangel; Rey, Helena Cramer; Lamas, Cristiane C.Introduction: Cardiac complications of COVID-19 are potentially life-threatening. The occurrence of myocardial injury in the context of COVID-19 is multifactorial and has generated increasing interest. Methods: A systematic review with a meta-analysis of the literature was performed. MEDLINE and EMBASE were searched. Two independent reviewers evaluated the selected manuscripts for the outcome “myocardial injury”, defined by troponin elevation above the 99th percentile. The study heterogeneity and risk of bias were evaluated. Results: Eight studies, with a total of 1,229 patients, were included. The frequency of myocardial injury was 16% (95% CI: 9%-27%). The heterogeneity among the studies was high (93%). Conclusions: Myocardial injury may occur in patients with COVID-19, with a frequency of 16% according to current studies. Continuous research is needed to update these findings as the pandemic evolves and to define the implications of myocardial injury in the context of this infection.
- ItemAcute coronary syndrome, a rare manifestation of infective endocarditis: a case report(Heart, Vessels and Transplantation, 2020) Tagliari, Fabio; Ribeiro, Caio Leal; Carvalho, Gabriel Padua Valladao de; Tagliari, Lais Pedroso; Weksler, Clara; Lamas, Cristiane da CruzSystemic embolization in infective endocarditis is common, occurring in 45-65% of cases. However, the septic coronary embolization is a complication rarely described as a cause of acute myocardial infarction (AMI). The presentation of chest pain as the first manifestation of endocarditis is associated with a poor prognosis. Mitral valve endocarditis with embolization to the left anterior descending coronary is the most common situation described in the literature. We present a case of a young male patient with typical angina caused by acute myocardial infarction, who had an obstructive lesion to the marginal branch of the circumflex artery in the angiography, and was later diagnosed with aortic valve endocarditis.